LOS ANGELES, CALIFORNIA - OCTOBER 31: Jayden Maiava #14 of the USC Trojans throws a pass against the Ohio State Buckeyes during the first quarter at Los Angeles Memorial Coliseum on October 31, 2026 in Los Angeles, California. (Photo by Luke Hales/Getty Images)

USC-Indiana Betting Line Movement Raises QB Injury Concern

LOS ANGELES, CALIFORNIA - SEPTEMBER 26: Head coach Lincoln Riley of the USC Trojans looks on during a game against the Oregon Ducks at Los Angeles Memorial Coliseum on September 26, 2026 in Los Angeles, California. (Photo by Ben Liebenberg/Getty Images)

LOS ANGELES, CALIFORNIA – SEPTEMBER 26: Head coach Lincoln Riley of the USC Trojans looks on during a game against the Oregon Ducks at Los Angeles Memorial Coliseum on September 26, 2026 in Los Angeles, California. (Photo by Ben Liebenberg/Getty Images) Getty

The USC and Indiana college football betting line moved dramatically on Wednesday afternoon.

On one sportsbook, it moved

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